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Human Glucagon-Like Peptide-1
Name：
Human Glucagon-Like Peptide-1
Category：
Molecular Weight：
3355.72
Molecular Formula：
C151H228N40O47
CAS NO：
106612-94-6
Sequence：
NH2-HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG-COOH
Functions and Effects：
GLP-1 is an incretin hormone mainly secreted by intestinal L cells. It specifically binds to GLP-1 receptors (GLP-1R) on the surface of pancreatic islet β cells, activating adenylate cyclase, which increases intracellular cAMP levels, thereby activating protein kinase A (PKA) and promoting insulin secretion. At the same time, GLP-1 can inhibit glucagon secretion, reduce hepatic glucose output, delay gastric emptying, increase satiety, and reduce food intake. Additionally, it may have protective and proliferative effects on pancreatic islet β cells, improving their function.
Molecular Structure Formula：
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